Discovery of the ten-eleven translocation 1 (TET) methylcytosine dioxygenase family of enzymes. nearly 10 years ago. heralded a major breakthrough in understanding the epigenetic modifications of DNA. Initially described as catalyzing the oxidation of methyl cytosine (5mC) to hydroxymethyl cytosine (5hmC). https://usoneilles.shop/product-category/mens/