Inside The absence of this enzyme, as in Crigler-Najjar syndrome sort I, the amounts of unconjugated bilirubin will rise, resulting in jaundice. Unconjugated bilirubin is water-insoluble, and higher ranges can deposit during the brain leading to a situation known as kernicterus. Severe hyperbilirubinemia normally develops in the primary number of https://www.youtube.com/shorts/IuPMi7CvqAo